释义 |
dermatochalasis
der·ma·to·cha·la·sis (der'mă-tō-kă-lā'sis), A congenital or acquired condition characterized by deficient elastic fibers of the skin, which may hang in folds; vascular anomalies may be present; inheritance is either autosomal dominant or recessive, the latter sometimes in association with pulmonary emphysema and diverticula of the alimentary tract or bladder. The dominant form is caused by mutation in the elastin gene (ELN) on 7q. There is also an X-linked form that is due to mutation in the Menkes gene (MNK), encoding copper-transporting ATPase on Xq. Synonym(s): cutis laxa, generalized elastolysis, loose skin [dermato- + G. chalasis, a loosening] der·ma·to·cha·la·sis (dĕr'mă-tō-kal'ă-sis) An acquired condition characterized by undue looseness or pendulousness of the eyelid skin due to degeneration of elastic fibers. Synonym(s): cutis laxa [TA] , pachydermatocele, blepharochalasis. [dermato- + G. chalasis, a loosening]dermatochalasis (dĕr″mă-tō-kă-lā′sĭs) [ dermato- + Gr. chalasis, relaxation] Loose or sagging soft tissue in the eyelids, esp. the upper eyelid. It results from loss of tissue elasticity and is more prevalent in older people. dermatochalasisA condition in which there is a redundancy of the skin of the upper eyelids. It is often associated with a protrusion of fat through a defective orbital septum. The condition occurs usually in old people. The excess skin may cause pseudoptosis. In severe cases it may obstruct vision. Treatment is surgical. Syn. ptosis adiposa; ptosis atrophica. See blepharochalasis. |