Chlordecone

A carcinogenic chlorinated polycyclic ketone insecticide and fungicide used in the US between 1966 and 1975. It gained notoriety from its improper handling and dumping into the James River, Virginia, which was subsequently closed to fishing. Chlordecone has a 30-year environmental half-life
Toxicity Tremors, nystagmus, memory loss, headaches, slurred speech, unsteadiness, incoordination, loss of weight, rash, hepatomegaly, decreased libido, sterility, chest pain, arthralgia, and the increased risk of cancer