chlormethine
mechlorethamine
A nitrogen mustard derivative which binds to DNA, crosslinking both strands to prevent its replication.Global village
Mechlorethamine was first developed as a chemical weapon.
Oncology
A nitrogen mustard alkylating agent used for managing lymphomas; part of MOPP.
Adverse effects
Nausea, vomiting, marrow suppression, skin vesiculation at injection site.