chlormethine


mechlorethamine

A nitrogen mustard derivative which binds to DNA, crosslinking both strands to prevent its replication.
Global village
Mechlorethamine was first developed as a chemical weapon.
Oncology
A nitrogen mustard alkylating agent used for managing lymphomas; part of MOPP.
 
Adverse effects
Nausea, vomiting, marrow suppression, skin vesiculation at injection site.

chlormethine

An alkylating drug that has been used to treat cancer. It is very toxic and causes severe vomiting. The drug is on the WHO official list.