cholesterol embolization syndrome

cholesterol embolization syndrome

Atheroembolic renal disease Vascular disease A condition affecting ± 4/10,000, more common in ♂ ≥ age 60, in which showers of cholesterol and debris from atherosclerotic plaques embolize to renal arterioles, blocking blood flow, resulting in renal infarction and possibly renal failure Risk factors ASHD, DM, HTN, smoking, obesity, hyperlipidemia. See Atherosclerotic heart disease.

cholesterol embolization syndrome

The systemic consequences that result from the splintering of cholesterol-containing plaques from the aorta; when this occurs fragments of cholesterol crystals may travel to and obstruct blood vessels throughout the body. The renal, mesenteric, and femoral arteries are most often affected; involvement of the cerebral vessels is unusual. This condition may arise after trauma to the aorta (e.g., during catheterization or cardiac surgery). It may produce renal failure, and ischemia or infarction of the bowel, toes, or skin. It may ultimately result in death in about half of all affected patients. There is no effective treatment.