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chon·dro·myx·oid fi·bro·maan uncommon benign bone tumor, occurring most frequently in the tibia of adolescents and young adults, composed of lobulated myxoid tissue with scanty chondroid foci. Synonym(s): chondrofibroma, chondromyxomachondromyxoid fibroma A focally aggressive tumour which arises in the femoral and proximal tibial metaphyses of young (< age 30) adults. Imaging Eccentric, punched out lytic lesion with peripheral sclerosis; it may extend into soft tissue.chon·dro·myx·oid fi·bro·ma , chondromyxoma (kon'drō-miks'oyd fī-brō'mă, kon'drō-mik-sō'mă) An uncommon benign bone tumor, occurring most frequently in the tibia of adolescents and young adults, composed of lobulated myxoid tissue with scanty chondroid foci. Synonym(s): chondrofibroma. |