bone marker

bone marker

Any biochemical marker that indicates bone breakdown, which can be used to predict individual fracture risk when bone mineral density measurement does not provide a clear answer.
Bone markers
Bone formation markers
• Serum total alkaline phosphatase;
• Serum bone—specific alkaline phosphatase;
• Serum osteocalcin;
• Serum type-1 procollagen.
Bone resorption markers
• Urine hydroxyproline;
• Urine total pyridinoline (PYD);
• Urine free deoxypyridinoline (DPD);
• Urine collagen type-1 cross-linked N-telopeptide (NTX);
• Urine or serum collagen type-1 cross-linked C-telopeptide (CTX);
• Bone sialoprotein (BSP);
• Tartrate-resistant acid phosphatase 5b.

bone marker

Lab medicine Any protein degradation product that indicates bone breakdown. See N-telopeptides.