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单词 darier's disease
释义

Darier's disease


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Noun1.Darier's disease - a rare hereditary condition marked by dark crusted patches (sometimes containing pus)keratosis folliculariskeratosis - a skin condition marked by an overgrowth of layers of horny skin
EncyclopediaSeekeratosis

Darier's disease


keratosis

 [ker″ah-to´sis] any horny growth, such as a wart or callosity.actinic keratosis a sharply outlined wartlike or keratotic growth, which may develop into a cutaneous horn, and may become malignant; it usually occurs in the middle aged or elderly and is due to excessive exposure to the sun. Called also senile or solar keratosis. (See Atlas 3, Part F).keratosis follicula´ris a slowly progressive autosomal dominant disorder of keratinization characterized by pinkish to tan or skin-colored papules on the seborrheic areas of the body that coalesce to form plaques, which may become crusted and secondarily infected; over time, the lesions may become darker and may fuse to form papillomatous and warty malodorous growths. Called also Darier's disease and Darier-White disease.keratosis palma´ris et planta´ris palmoplantar keratoderma.keratosis pharyn´gea horny projections from the tonsils and pharyngeal walls. Called also pharyngokeratosis.keratosis pila´ris hyperkeratosis limited to the hair follicles.keratosis puncta´ta a hereditary hyperkeratosis in which the lesions are localized in multiple points on the palms and soles.seborrheic keratosis (keratosis seborrhe´ica) a benign, noninvasive tumor of epidermal origin, marked by numerous yellow or brown, sharply marginated, oval, raised lesions.senile keratosis (solar keratosis) actinic keratosis.

Darier's disease

Keratosis follicularis, a rare autosomal dominant skin disease caused by mutations on Chromosome 12. It features warty, foul-smelling plaques formed of coalesced greasy plaques of seborrhoeic dermatitis with severe itching and sometimes pain. The disease is chronic and may worsen with age. Treatment is with oral retinoids. Prenatal diagnosis by DNA analysis of cells obtained by chorionic villus sampling is possible.

Darier's disease


Related to Darier's disease: lichen planus
  • noun

Synonyms for Darier's disease

noun a rare hereditary condition marked by dark crusted patches (sometimes containing pus)

Synonyms

  • keratosis follicularis

Related Words

  • keratosis
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