equivalence trial

A clinical trial with the primary objective of showing that the response to two or more treatments differs by an amount that is clinically insignificant, which is usually demonstrated by showing that the true treatment difference lies between a lower and an upper equivalence margin of clinically acceptable differences.

equivalence trial

Clinical trials A study–eg, COBALT, intended to circumvent the ethical dilemmas of comparing a new therapy to a placebo which is known to be less effective than a proven therapy, by running the new agent against a standard therapy. See Clinical trial, COBALT.

equivalence trial

A randomized clinical trial in which two distinct agents are compared head-to-head against each other, and sometimes, but not always, against an inert agent (a placebo) as well. If two agents work equally well, the treatment that is less expensive, better tolerated, or more easily administered, may be preferable to use.

equivalence trial

A randomized clinical trial in which two distinct agents are compared with each other and sometimes with an inert agent (a placebo) as well. If two agents work equally well, the less expensive, better tolerated, or more easily administered one may be preferred. See also: trial

单词	equivalence trial
释义	DictionarySeetrial equivalence trial equivalence trial A clinical trial with the primary objective of showing that the response to two or more treatments differs by an amount that is clinically insignificant, which is usually demonstrated by showing that the true treatment difference lies between a lower and an upper equivalence margin of clinically acceptable differences. equivalence trial Clinical trials A study–eg, COBALT, intended to circumvent the ethical dilemmas of comparing a new therapy to a placebo which is known to be less effective than a proven therapy, by running the new agent against a standard therapy. See Clinical trial, COBALT. equivalence trial A randomized clinical trial in which two distinct agents are compared head-to-head against each other, and sometimes, but not always, against an inert agent (a placebo) as well. If two agents work equally well, the treatment that is less expensive, better tolerated, or more easily administered, may be preferable to use. equivalence trial A randomized clinical trial in which two distinct agents are compared with each other and sometimes with an inert agent (a placebo) as well. If two agents work equally well, the less expensive, better tolerated, or more easily administered one may be preferred. See also: trial LegalSeeTrial
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