| 释义 |
cardioselectivity car·di·o·se·lec·tiv·i·ty (kar'dē-ō-sĕ-lek-tiv'i-tē), The relatively predominant cardiovascular pharmacologic effect of a drug with multipharmacologic effects; used especially when describing beta-blocking agents.car·di·o·se·lec·tiv·i·ty (kahr'dē-ō-sĕ-lek-tiv'i-tē) The relatively predominant cardiovascular pharmacologic effect of a drug with multipharmacologic effects; used especially when describing beta-blocking agents. cardioselectivity (kard?e-o-se?lek?tiv'it-e) [ cardio- + L. seligere, to separate, select] A stronger action on receptors in the heart than on those in the lungs. It is said of beta-adrenergic blocking agents that selectively block beta-1 receptors and thus do not cause bronchospasm. Patient carePatients with asthma or chronic obstructive pulmonary disease (COPD) should avoid high doses of nonselective beta-adrenergic drugs (beta blockers) because they can cause wheezing and shortness of breath. Patients with mild or moderate obstructive lung disease can safely use cardioselective beta blockers. See: beta-adrenergic blocking agentcardioselective (kard?e-o-se?lek'tiv), adjective |