英语词汇“chromatin assembly factor-1”的英英意思、用法、释义、翻译、读音、例句、短语、词组-英语词典

单词	chromatin assembly factor-1
释义	chromatin assembly factor-1 chromatin assembly factor-1 A protein encoded by CHAF1A on chromosome 19p13.3 that is critical for maintaining chromatin stability during DNA replication and repair. Abnormal expression CAF-1 is overexpressed in solid tumours—e.g., endometrium, uterine cervix, breast and renal. In most, CAF-1 overexpression is associated with a higher histologic grade and clinical stage, and is regarded as a predictor of adverse outcomes.
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