To cause one to experience sadness, hopelessness, and/or frustration. I'm not surprised that his wife's death has driven him to despair—grief has that effect on people.Try not to let this rejection drive you to despair.See also: despair, drive
drive someone to despair
Fig. to depress someone; to frustrate someone. Sometimes raising an infant drives me to despair!The recent problems drove her to despair.See also: despair, drive