becaplermin


becaplermin

 [bĕ-kap´ler-min] a recombinant factor" >platelet-derived growth factor used in treatment of chronic severe dermal ulcers of the lower limbs in diabetes mellitus.

becaplermin

A cicatrizant gel containing recombinant PDGF, which may improve wound healing—it stimulates migration of cells to ulcer sites, and prompts tissue growth to heal deep open wounds.
 
Indication
Diabetic foot ulcers.
 
Cons
Expensive, increased risk of cancer.

becaplermin

Recombinant human platelet-derived growth factor used to promote the healing of leg ulcers, especially in diabetics. A brand name is Regranex.