| 释义 |
disulfiram
di·sul·fi·ram D0297850 (dī-sŭl′fə-răm′)n. A drug used in the treatment of alcoholism that interferes with the metabolic degradation of alcohol, producing an unpleasant reaction when even a small quantity of alcohol is consumed.
[disulfi(de) + (thiu)ram, one of its constituents (thi(o)- + ur(ea) + am(ide)).]disulfiram (ˌdaɪsʌlˈfɪərəm) n (Pharmacology) a drug used in the treatment of alcoholism that acts by inducing nausea and other unpleasant effects following ingestion of alcohol[C20: from tetraethylthiuram disulfide]Thesaurus| Noun | 1. |  disulfiram - a drug (trade name Antabuse) used in the treatment of alcoholism; causes nausea and vomiting if alcohol is ingestedAntabusemedicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease |
TranslationsDisulfiram
disulfiram[di′səl·fə‚ram] (pharmacology) C10H20N2S4 A drug used to treat alcohol abuse that blocks the metabolism of acetaldehyde, the major metabolite of ethanol, causing a rapid buildup of acetaldehyde and a severe physiological syndrome intended to prevent or modify further immediate drinking behavior. Also known as Antabuse. Disulfiram (also teturamin, Antabuse), a drug used to treat alcoholism. Disulfiram inhibits the oxidation of alcohol, causing acetic aldehyde to accumulate. As a result, the consumption of alcohol leads to such symptoms as sensation of heat, tightness in the chest, heart palpitations, anxiety, and vomiting. Disulfiram is taken orally in the form of tablets. Treatment is first undertaken in a hospital. disulfiram
disulfiram [di-sul´fĭ-ram] Antabuse; a compound that, when used in the presence of alcohol, produces distressing symptoms such as severe nausea and vomiting. It is a dangerous drug, should always be given under the supervision of a physician and is never given to a patient who is in a state of intoxication or does not have full knowledge of its effects. Disulfiram inhibits the oxidation of acetaldehyde produced by the metabolism of alcohol; the resultant accumulation of acetaldehyde in the body is what causes nausea, vomiting, palpitation, dyspnea, and lowered blood pressure. Occasionally this may lead to profound collapse.di·sul·fi·ram (dī-sŭl'fi-ram), An antioxidant that interferes with the normal metabolic degradation of alcohol in the body, resulting in increased acetaldehyde concentrations in blood and tissues. Used in the treatment of chronic alcoholism; when taken regularly in chronic alcoholism, it can lower the risk of relapse by inducing severe malaise and nausea if alcohol is consumed. Also used as a chelator in copper and nickel poisoning. Synonym(s): tetraethylthiuram disulfidedisulfiram (dī-sŭl′fə-răm′)n. A drug used in the treatment of alcoholism that interferes with the metabolic degradation of alcohol, producing an unpleasant reaction when even a small quantity of alcohol is consumed.disulfiram Antabuse® An antioxidant that interferes with alcohol metabolism, resulting in ↑ acetaldehyde concentrations; it is effective in treating alcoholism as it produces aversive symptoms if combined with alcoholdi·sul·fi·ram (dī-sŭl'fi-ram) An antioxidant that interferes with the normal metabolic degradation of alcohol in the body, resulting in increased acetaldehyde concentrations in blood and tissues. Used in the treatment of chronic alcoholism; when taken regularly in chronic alcoholism, it can lower the risk of relapse by inducing severe malaise and nausea if alcohol is consumed. Also used as a chelator in copper and nickel poisoning. disulfiram A drug that interferes with the normal metabolism of alcohol so that a toxic substance, acetaldehyde, accumulates. This causes flushing, sweating, nausea, vomiting, faintness, headache, chest pain and sometimes convulsions and collapse. It is sometimes used to discourage drinking, but is not without danger. A brand name is Antabuse.disulfiram
Synonyms for disulfiramnoun a drug (trade name Antabuse) used in the treatment of alcoholismSynonymsRelated Words- medicament
- medication
- medicinal drug
- medicine
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