单词 | complement cascade |
释义 | complement cascadecomplement cascade[′käm·plə·mənt kas′kād]complement cascadecomplement cascadeImmunology A complex, multimolecular biologic system with ± 25 different proteins that self-assemble on cell surfaces, functioning in concert with the specific immune systems to mediate host reactions and anti-microbial defense; the coup de grâce for the hapless target cell is the polymerization of C9 on its surface, which forms a transmembrane 'doughnut' that facilitates the egress of ions, cell lysis and death. See Complement. Cf Alternate pathway, Classic pathway, Common pathway. |
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