CASP7

A gene on chromosome 10q25 that encodes a protein belonging to the cysteine-aspartic acid protease (caspase) family which, once activated by proteolytic processing, plays a central role in the execution phase of apoptosis. Effector (also called executioner) caspases CASP3, -6 and -7 are responsible for cleaving downstream substrates—CASP7 cleaves and activates sterol regulatory element binding proteins (SREBPs). It is highly expressed in the lung, skeletal muscle, liver, kidney, spleen and heart.

单词	casp7
释义	CASP7 CASP7 A gene on chromosome 10q25 that encodes a protein belonging to the cysteine-aspartic acid protease (caspase) family which, once activated by proteolytic processing, plays a central role in the execution phase of apoptosis. Effector (also called executioner) caspases CASP3, -6 and -7 are responsible for cleaving downstream substrates—CASP7 cleaves and activates sterol regulatory element binding proteins (SREBPs). It is highly expressed in the lung, skeletal muscle, liver, kidney, spleen and heart.
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