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bradykininenUK
brad·y·ki·nin B0444700 (brăd′ĭ-kī′nĭn, -kĭn′ĭn)n. A biologically active polypeptide, consisting of nine amino acids, that forms from a blood plasma globulin and mediates the inflammatory response, increases vasodilation, and causes contraction of smooth muscle.
[brady- + Greek kīnein, to move; see keiə- in Indo-European roots + -in.]bradykinin (ˌbrædɪˈkaɪnɪn; ˌbreɪdɪ-) n (Physiology) a peptide in blood plasma that dilates blood vessels and causes contraction of smooth muscles. Formula: C50H73N15O11[C20: from brady- + Greek kin(ēsis) motion + -in]brad•y•kin•in (ˌbræd ɪˈkɪn ɪn, -ˈkaɪ nɪn)
n. a peptide hormone that dilates blood vessels and increases capillary permeability. [1945–50] bradykininenUK
bradykinin[¦brād·i′kī·nən] (biochemistry) C50H73N15O11 A polypeptide kinin; forms an amorphous precipitate in glacial acetic acid; released from plasma precursors by plasmin; acts as a vasodilator. Also known as callideic I; kallidin I. bradykininenUK
bradykinin [brad″e-ki´nin] a nonapeptide kinin formed from a plasma protein, high-molecular-weight (HMW) kininogen by the action of kallikrein; it is a very powerful vasodilator that increases capillary permeability and, in addition, constricts smooth muscle and stimulates pain receptors.bra·dy·ki·nin (brad'ē-kī'nin), The nonapeptide Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg, produced from the decapeptide kallidin (bradykininogen) that is produced from α2-globulin by kallikrein, normally present in blood in an inactive form and similar to trypsin in action; bradykinin is one of several plasma kinins, is a potent vasodilator, and is one of the physiologic mediators of anaphylaxis released from cytotropic antibody-coated mast cells following reaction with antigen (allergen) specific for the antibody. Synonym(s): kallidin 9, kallidin I, kinin 9 [brady- + G. kineō, to move] bradykinin (brăd′ĭ-kī′nĭn, -kĭn′ĭn)n. A biologically active polypeptide, consisting of nine amino acids, that forms from a blood plasma globulin and mediates the inflammatory response, increases vasodilation, and causes contraction of smooth muscle.bradykinin A vasoactive nonapeptide (RPPGFSPFR) formed by action of proteases on kininogens, which is very similar to kallidin (the same sequence, but with an additional N terminal lysine). It is a potent vasodilator, increasing the permeability of postcapillary venules and acting on endothelial cells to activate phospholipase A2; it is also spasmogenic for some smooth muscle and evokes pain.bra·dy·ki·nin (brad'ē-kī'nin) The nonapeptide Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg, normally present in blood in an inactive form; one of the plasma kinins, a potent vasodilator and mediator of anaphylaxis. [brady- + G. kineō, to move]bradykinin A peptide that widens blood vessels (vasodilatation) and lowers blood pressure, increases capillary permeability and the secretion of saliva and mediates pain associated with inflammation. Bradykinin is inactivated by the angiotensin-converting enzyme.bradykinin a hormone formed from a kininogen in the blood plasma that has the effect of rapid VASODILATION in the skin.bra·dy·ki·nin (brad'ē-kī'nin) One of several plasma kinins, a potent vasodilator; physiologic mediator of anaphylaxis released from cytotropic antibody-coated mast cells following reaction with antigen (allergen) specific for the antibody. [brady- + G. kineō, to move]AcronymsSeeblinker |