| 释义 |
creatine
cre·a·tine C0733600 (krē′ə-tēn′, -tĭn) also cre·a·tin (-tĭn)n. A compound, C4H9N3O2, that is found in the muscle tissue of vertebrates mainly in the form of phosphocreatine and that is involved in the storing and supplying energy for muscle contraction.
[French créatine : from Greek kreas, kreat-, flesh; see kreuə- in Indo-European roots.]creatine (ˈkriːəˌtiːn; -tɪn) or creatinn (Biochemistry) an important metabolite involved in many biochemical reactions and present in many types of living cells[C19: creat- from Greek kreas flesh + -ine2]cre•a•tine (ˈkri əˌtin, -tɪn)
n. an amino acid, C4H9N3O2, that is a constituent of the muscles of vertebrates and is phosphorylated to store energy used for muscular contraction. [1830–40; creat- (< Greek kreat-, s. of kréas) flesh + -ine2] Thesaurus| Noun | 1. | creatine - an amino acid that does not occur in proteins but is found in the muscle tissue of vertebrates both in the free form and as phosphocreatine; supplies energy for muscle contractioncreatinamino acid, aminoalkanoic acid - organic compounds containing an amino group and a carboxylic acid group; "proteins are composed of various proportions of about 20 common amino acids" |
TranslationsCreatine
creatine[′krē·ə‚tēn] (biochemistry) C4H9O2N3α-Methylguanidine-acetic acid; a compound present in vertebrate muscle tissue, principally as phosphocreatine. Creatine N-methylguanidoacetic acid. Molecular weight, 131.14; melting point, 315°C (with dissociation): 
Creatine is soluble in hot water, slightly soluble in alcohol, and insoluble in ether. The interaction of mineral acids and creatine produces the lactam creatinine. This reaction is the basis of one of the methods used to determine creatine content. Creatine dissociates into urea and methylglycine in an alkaline medium. Creatine was discovered in 1835 by the French scientist M. Chevreul in extracts from skeletal muscles. It is found in the muscle tissue of all vertebrates (approximately 0.5 percent of the muscle weight) in the form of the unstable creatinephosphoric acid, which takes part in supplying the energy required for muscle contraction. Smaller quantities are present in nerve tissue, blood, liver, and kidneys. Creatine biosynthesis in an organism is achieved in the kidneys from the amino acids glycine and arginine, forming glycocyamine. The glycocyamine undergoes subsequent methylation in the liver in the presence of the amino acid methionine to yield creatine. N. P. MESHKOVA creatine
creatine [kre´ah-tin] a nonprotein substance synthesized in the body from three amino acids: arginine, glycine (aminoacetic acid), and methionine. Creatine readily combines with phosphate to form phosphocreatine, or creatine phosphate, which is present in muscle, where it serves as the storage form of high-energy phosphate necessary for muscle contraction.creatine kinase an enzyme catalyzing the transfer of a phosphate group from phosphocreatine to ATP. It has three isoenzymes: CK1, found primarily in the brain; CK2, found in the myocardium; and CK3, found in both skeletal muscle and the myocardium. The presence of CK2 in the blood is strongly indicative of a recent myocardial infarction; it is present until about 72 hours after the attack.cre·a·tine (krē'ă-tēn, -tin), Do not confue this word with creatinine.A compound, N-(aminoiminomethyl)-N-methylglycine, which occurs in urine, sometimes simply as creatine, but generally as creatinine, and in muscle, generally as phosphocreatine. Elevated levels are found in the urine of individuals with muscular dystrophy.creatine (krē′ə-tēn′, -tĭn) also creatin (-tĭn)n. A compound, C4H9N3O2, that is found in the muscle tissue of vertebrates mainly in the form of phosphocreatine and that is involved in storing and supplying energy for muscle contraction.cre·a·tine (krē'ă-tin) N-(aminoiminomethyl) - N-methylglycine; occurs in urine, sometimes as such, but generally as creatinine, and in muscle, generally as phosphocreatine; elevated in urine in muscular dystrophy; synthesized in liver and pancreas from amino acids; absorbed in bloodstream, it is deposited in tissue (e.g., muscles, brain). creatine A nitrogenous substance present in all muscle cells.creatine a white nitrogenous substance found in vertebrate muscles.Patient discussion about creatineQ. Q. I want to know about urine protein creatine ratio in diagnosing nephrotic syndrome. Please explain interms of unit such as mg/mg or mmol/mg. Normal range, nephrotic range with good referrence.A. Nephrotic syndrome is defines as a damage to the kidneys, in which there is a leak of large amounts of protein (over 3.5 grams of protein / 24 hours urine output) from the blood to the urine. Protein loss causes low protein count in the blood (hypoalbuminemia) and edemas (excess fluid in the interstitial cavity which is between the cells, causes leg swelling most often, and also in the adbomen and around the eyes). More discussions about creatineFinancialSeeCKSee CREA
See CREAcreatine
Related to creatine: creatinineSynonyms for creatinenoun an amino acid that does not occur in proteins but is found in the muscle tissue of vertebrates both in the free form and as phosphocreatineSynonymsRelated Words- amino acid
- aminoalkanoic acid
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