| 释义 |
creatine kinase
creatine kinasen. An enzyme present in muscle, brain, and other tissues of vertebrates that catalyzes the reversible conversion of ADP and phosphocreatine into ATP and creatine.creatine kinase
creatine kinase[¦krē·ə‚tēn ′kī‚nās] (biochemistry) An enzyme of vertebrate skeletal and myocardial muscle that catalyzes the transfer of a high-energy phosphate group from phosphocreatine to adenosine diphosphate with the formation of adenosine triphosphate and creatine. creatine kinase
creatine [kre´ah-tin] a nonprotein substance synthesized in the body from three amino acids: arginine, glycine (aminoacetic acid), and methionine. Creatine readily combines with phosphate to form phosphocreatine, or creatine phosphate, which is present in muscle, where it serves as the storage form of high-energy phosphate necessary for muscle contraction.creatine kinase an enzyme catalyzing the transfer of a phosphate group from phosphocreatine to ATP. It has three isoenzymes: CK1, found primarily in the brain; CK2, found in the myocardium; and CK3, found in both skeletal muscle and the myocardium. The presence of CK2 in the blood is strongly indicative of a recent myocardial infarction; it is present until about 72 hours after the attack.cre·a·tine ki·nase (CK), an enzyme catalyzing the reversible transfer of phosphate from phosphocreatine to ADP, forming creatine and ATP; of importance in muscle contraction. Certain isozymes are elevated in plasma following myocardial infarctions. Synonym(s): creatine phosphokinasecreatine kinasen. An enzyme present in muscle, brain, and other tissues of vertebrates that catalyzes the reversible conversion of ADP and phosphocreatine into ATP and creatine.creatine kinase Creatine phosphokinase Internal medicine An 82 kD dimeric enzyme that catalyzes the reaction ATP + creatine = ADP + phosphocreatine, which exchanges high-energy phosphate and consumes energy; CK is concentrated in skeletal muscle, heart, brain; since CK levels peak 12-24 hrs after an MI and returns to normal by 48 hrs, specimen timing is critical Ref range 0-250 U/L. See Creatinine kinase isoenzymes. cre·a·tine ki·nase (CK) (krē'ă-tin kī'nās) An enzyme catalyzing the reversible transfer of phosphate from phosphocreatine to ADP, forming creatine and ATP; of importance in muscle contraction. Certain isozymes are elevated in plasma following myocardial infarctions. cre·a·tine ki·nase (CK) (krē'ă-tin kī'nās) An enzyme catalyzing the reversible transfer of phosphate from phosphocreatine to adenosine diphosphate, forming creatine and adenosine triphosphate. AcronymsSeeCKThesaurusSeecreatine |