Castle intrinsic factor


in·trin·sic fac·tor (IF),

a small mucoprotein (MW about 45,000) secreted by the neck cell of the gastric glands and required for adequate absorption of vitamin B12 and other cobalamins; deficiency results in pernicious anemia. Synonym(s): Castle intrinsic factor

Castle intrinsic factor

(kas'el) [William Bosworth Castle, U.S. physician and physiologist, 1897–1990] Intrinsic factor.

Castle,

William B., U.S. physician, 1897-1990. Castle intrinsic factor - a relatively small mucoprotein required for adequate absorption of vitamin B12. Synonym(s): intrinsic factor