allergic granulomatosis


granulomatosis

 [gran″u-lo″mah-to´sis] any condition involving the formation of multiple granulomas.allergic granulomatosis churg-strauss syndrome.eosinophilic granulomatosis Langerhans cell histiocytosis.Langerhans cell granulomatosis histiocytosis" >Langerhans cell histiocytosis.lymphomatoid granulomatosis a multisystem disease involving predominantly the lungs, skin, central nervous system, and kidneys, caused by invasion and destruction of vessels by atypical lymphoreticular cells. Many affected patients develop frank lymphoma. It usually affects males, and the most frequent presenting symptoms are cough, shortness of breath, and chest pain. Extrapulmonary manifestations are common, with skin lesions being present in many cases.granulomatosis sidero´tica a condition in which brownish nodules are seen in the enlarged spleen.Wegener's granulomatosis a multisystem disease chiefly affecting males, characterized by necrotizing granulomatous vasculitis involving the upper and lower respiratory tracts, glomerulonephritis, and variable degrees of systemic, small vessel vasculitis, which is generally considered to represent an aberrant hypersensitivity reaction to an unknown antigen.

Churg-·Strauss syn·drome

(chŭrg strows), asthma, fever, eosinophilia, and varied symptoms and signs of vasculitis, primarily affecting small arteries, with vascular and extravascular granulomas. Synonym(s): allergic granulomatosis, allergic granulomatous angiitis

Churg-Strauss syndrome

An autoimmune vasculitis of small to medium blood vessels with hypereosinophilia arising in a background of asthma and allergic rhinitis, which may be accompanied by tissue eosinophilia, peripheral neuropathy, gastrointestinal necrosis, cardiac lesions, and renal disease. Skin lesions are common in the form of purpura, erythema, urticaria and nodules arising on the scalp and/or extremities.

Churg,

Jacob, Polish-born U.S. pathologist, 1910–. Churg-Strauss syndrome - asthma, fever, eosinophilia, and varied symptoms and signs of vasculitis, primarily affecting small arteries, with vascular and extravascular granulomas. Synonym(s): allergic granulomatosis; allergic granulomatous angiitis; Strauss-Churg-Zak syndrome