| 单词 |
brca1 gene |
| 释义 |
DictionarySeegeneBRCA1 gene
BRCA1 genea tumor suppressor gene on chromosome 17 at locus 17q21, isolated in 1994; carriers of germline mutations in BRCA1 are predisposed to develop both breast and ovarian cancer.
See also: BRCA2 gene, carcinoma of the breast. BRCA1 gene (jēn) A tumor suppressor gene on chromosome 17 at locus 17q21, isolated in 1994; encodes p53 protein, which prevents cells with damaged DNA from dividing; carriers of germline mutations in BRCA1 are predisposed to develop both breast and ovarian cancer.
See also: BRCA2 gene, carcinoma of the breastBRCA1 geneA breast cancer gene found in a small percentage of patients with this malignancy, and carried by some individuals who will develop breast cancer later in life. Patient careBRCA1 Gene Mutation: Patient care focuses on determining the family history of the patient and referral to a genetic counselor with expertise in this mutation when appropriate. See also: gene |
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