| 释义 |
CREST complex CREST complex A pentad of clinical signs seen with mixed connective tissue disease: Calcinosis, Raynaud's phenomenon, Esophageal dysmotility with stricture, Sclerodactyly, Telangiectasia; CREST has a slightly better prognosis than other connective tissue disorders, but has late complications–eg, biliary cirrhosis and pulmonary HTN Lab Anticentromere antibodies are characteristic of CREST, but may be seen in progressive systemic sclerosis, older ♀, or with HLA-DR1. |