CREST syndrome

one of the less severe forms of scleroderma" >systemic scleroderma, consisting of calcinosis" >calcinosis of the skin, raynaud's phenomenon" >raynaud's phenomenon, esophageal dysfunction, sclerodactyly" >sclerodactyly, and telangiectasia" >telangiectasia. When esophageal dysfunction is not prominent, it is known as CRST syndrome.

CREST syn·drome

a variant of systemic sclerosis characterized by calcinosis, Raynaud phenomenon, esophageal motility disorders, sclerodactyly, and telangiectasia.

An acronym for the pentad of clinical signs seen with a limited form of scleroderma:
Calcinosis cutis
Raynaud’s phenomenon—at least a 2-phase colour change
Esophageal distal hypomotility or reflux esophagitis
Sclerodactyly or nonpitting digital edema
Telangiectasia; CREST has a slightly better prognosis than other connective tissue disorders, but has late complications—e.g., biliary cirrhosis and pulmonary hypertension
Lab Anticentromere antibodies are characteristic of CREST, but may also be seen in progressive systemic sclerosis, older women, or those with HLA-DR1

CREST syn·drome

(krest sin'drōm) An acronymic designation for a variant of scleroderma characterized by calcinosis, Raynaud phenomenon, esophageal motility disorders, sclerodactyly, and telangiectasia.

CREST syndrome

Acronym for a connective tissue disorder, related to progressive systemic sclerosis, but limited to CALCINOSIS, RAYNAUD'S PHENOMENON, oesophageal involvement, hardness of the fingers (Sclerodactyly) and dilated skin blood vessels (TELANGIECTASIA). The word forming the third letter of the acronym is spelt ‘esophageal’ in the USA.

Thibierge,

Georges, French physician, 1856-1926. Thibierge-Weissenbach syndrome - calcinosis, Raynaud phenomenon, esophageal motility disorders, sclerodactyly, and telangiectasia. Synonym(s): CREST syndrome

CREST syn·drome

(krest sin'drōm) Acronym for variant of systemic sclerosis characterized by calcinosis, Raynaud phenomenon, esophageal motility disorders, sclerodactyly, and telangiectasia.

单词	crest syndrome
释义	DictionarySeecrestEncyclopediaSeeScleroderma CREST syndrome CREST syndrome one of the less severe forms of scleroderma" >systemic scleroderma, consisting of calcinosis" >calcinosis of the skin, raynaud's phenomenon" >raynaud's phenomenon, esophageal dysfunction, sclerodactyly" >sclerodactyly, and telangiectasia" >telangiectasia. When esophageal dysfunction is not prominent, it is known as CRST syndrome. CREST syn·drome a variant of systemic sclerosis characterized by calcinosis, Raynaud phenomenon, esophageal motility disorders, sclerodactyly, and telangiectasia. An acronym for the pentad of clinical signs seen with a limited form of scleroderma: Calcinosis cutis Raynaud’s phenomenon—at least a 2-phase colour change Esophageal distal hypomotility or reflux esophagitis Sclerodactyly or nonpitting digital edema Telangiectasia; CREST has a slightly better prognosis than other connective tissue disorders, but has late complications—e.g., biliary cirrhosis and pulmonary hypertension Lab Anticentromere antibodies are characteristic of CREST, but may also be seen in progressive systemic sclerosis, older women, or those with HLA-DR1 CREST syn·drome (krest sin'drōm) An acronymic designation for a variant of scleroderma characterized by calcinosis, Raynaud phenomenon, esophageal motility disorders, sclerodactyly, and telangiectasia. CREST syndrome Acronym for a connective tissue disorder, related to progressive systemic sclerosis, but limited to CALCINOSIS, RAYNAUD'S PHENOMENON, oesophageal involvement, hardness of the fingers (Sclerodactyly) and dilated skin blood vessels (TELANGIECTASIA). The word forming the third letter of the acronym is spelt ‘esophageal’ in the USA. Thibierge, Georges, French physician, 1856-1926. Thibierge-Weissenbach syndrome - calcinosis, Raynaud phenomenon, esophageal motility disorders, sclerodactyly, and telangiectasia. Synonym(s): CREST syndrome CREST syn·drome (krest sin'drōm) Acronym for variant of systemic sclerosis characterized by calcinosis, Raynaud phenomenon, esophageal motility disorders, sclerodactyly, and telangiectasia. FinancialSeeCrestThesaurusSeescleroderma
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