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DictionarySeeglomerulosclerosisdiabetic glomerulosclerosis
diabetic glomerulosclerosis[¦dī·ə¦bed·ik glə¦mər·yə·lō·sklə′rō·səs] (pathology) intercapillary glomerulosclerosis diabetic glomerulosclerosis
glomerulosclerosis [glo-mer″u-lo-sklĕ-ro´sis] arteriolar nephrosclerosis.diabetic glomerulosclerosis (intercapillary glomerulosclerosis) a degenerative complication of diabetes mellitus in which there is glomerular mesangial expansion with either diffuse lesions or nodular (Kimmelstiel-Wilson) lesions; symptoms include albuminuria, nephrotic edema, hypertension, renal insufficiency, and retinopathy. The type with nodular lesions is also called Kimmelstiel-Wilson syndrome.focal segmental glomerulosclerosis focal sclerosing lesions of the renal glomeruli, with proteinuria, hematuria, hypertension, and the nephrotic syndrome" >nephrotic syndrome; it may be idiopathic or secondary to another condition. Called also focal glomerular sclerosis.di·a·bet·ic glo·mer·u·lo·scle·ro·sisproteinuria and ultimately, renal failure occuring in long-standing diabetes, and characterized by rounded hyaline or laminated nodules in the periphery of the glomeruli with capillary basement membrane thickening, and increased mesangial matrix.Synonym(s): intercapillary glomerulosclerosis Synonym(s): intercapillary glomerulosclerosisdi·a·bet·ic glo·mer·u·lo·scler·o·sis (dī-ă-bet'ik glŏ-mer'yū-lō-skler-ō'sis) Rounded hyaline or laminated nodules in the periphery of the glomeruli with capillary basement membrane thickening and increased mesangial matrix occurring in long-standing diabetes, proteinuria, and ultimately renal failure.
Synonym(s): intercapillary glomerulosclerosis. diabetic glomerulosclerosisA type of glomerulosclerosis seen in some cases of diabetes mellitus. Eosinophilic material is present in various parts of the glomerulus. Synonym: intercapillary glomerulosclerosisSee also: glomerulosclerosis |