John F., U.S. physician, 1919–. Crigler-Najjar disease - Synonym(s): Crigler-Najjar syndromeCrigler-Najjar syndrome - a rare defect in ability to form bilirubin glucuronide due to deficiency of bilirubin-glucuronide glucuronosyltransferase. Synonym(s): Arias syndrome; Crigler-Najjar disease