DSG2
DSG2
A gene on chromosome 18q12.1 that encodes desmoglein 2, a calcium-binding transmembrane glycoprotein component of desmosomes expressed in the colon, in colorectal carcinoma, and in other simple and stratified epithelial-derived cell lines.Molecular pathology
Defects in DSG2 cause arrhythmogenic right ventricular dysplasia, type 10, and susceptibility to cardiomyopathy dilated type 1BB.