单词 | dst | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
释义 | DSTDSTDSTDSTor D.S.T.,DSTDstDSTDST(1) (DeSTination) Contrast with SRC, which is an abbreviation of "source."(2) (Digital Signal Trust Company, Salt Lake City, UT) An organization that set up and managed PKI systems for companies and industry groups. Using third-party software, DST served as a certification authority (CA), managed the repository and provided a secure location for the private keys. Founded in 1996, Utah-based DST was the first licensed CA in the U.S. and the first PKI service organization, and Utah was the first state to pass digital signature legislation. In 2002, DST was acquired by Identrus LLC (www.identrus.com), a global leader in digital trust services and secure e-commerce. See PKI. (3) (Data Storage Technology) An earlier high-capacity magnetic tape technology from Ampex that was based on the digital composite D2 format for the broadcasting industry. It used the same 19mm, helical scan transport, but provided higher capacities with Ampex's proprietary Data D-2 (DD2) format. DST cartridges ranged from 50 to 330GB. Ampex's Data Instrumentation Systems (DIS) tape technology was a counterpart line that provided optional modes and interfaces for data acquisition devices. See magnetic tape.
DSTDSTA gene on chromosome 6p12.1 that encodes dystonin, a cytoskeletal linker protein which integrates intermediate filaments, actin and the microtubule cytoskeleton network, and is required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional reticulum.DST isoform 3 plays a structural role in assembling hemidesmosomes of epithelial cells; it anchors keratin-containing intermediate filaments to the inner plaque of hemidesmosomes and is required for regulating keratinocyte polarity and motility; it mediates integrin ITGB4 regulation of RAC1 activity. DST isoform 6 is required for bundling actin filaments around the nucleus. DST isoform 7 regulates the organisation and stability of the microtubule network of sensory neurons to allow axonal transport. Molecular pathology Defects of DST cause hereditary sensory and autonomic neuropathy type 6. DST
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