Crooke granules

Crooke gran·ules

(kruk), lumpy masses of basophilic material in the basophil cells of the anterior lobe of the pituitary, associated with Cushing disease, or following the administration of ACTH.

Crooke gran·ules

(kruk gran'yūlz) Lumpy masses of basophilic material in the basophil cells of the anterior lobe of the pituitary, associated with Cushing disease, or following the administration of adrenocorticotropic hormone.

Crooke,

Arthur Carleton, English pathologist, 1905–. Crooke granules - lumpy masses of basophilic material in the pituitary associated with Cushing disease or following the administration of ACTH.Crooke hyaline change - replacement of cytoplasmic granules of basophil cells of the anterior pituitary by homogenous hyaline material. Synonym(s): Crooke hyaline degenerationCrooke hyaline degeneration - Synonym(s): Crooke hyaline change