CD49f

a type I transmembrane protein present on platelets, macrophages, monocytes, thymocytes, T cells, and adherent cell lines that forms a receptor for invasion and laminin; expressed in some acute lymphocytic leukemias.

ITGA6

A gene on chromosome 2q31.1 that encodes an integrin alpha chain protein which, like all integrins, forms a heterodimer with a beta chain, thereby participating in an array of cell-cell and cell-matrix interactions, playing a major role in cell migration, organ and tissue development, differentiation and metastases. Alpha 6 binds to a beta-1 chain, forming the VLA-6 integrin, a receptor for laminin on platelets, or with beta 4 to form TSP180, a receptor for laminin in epithelial cells, which plays a critical structural role in hemidesmosome.

单词	cd49f
释义	CD49f CD49f a type I transmembrane protein present on platelets, macrophages, monocytes, thymocytes, T cells, and adherent cell lines that forms a receptor for invasion and laminin; expressed in some acute lymphocytic leukemias. ITGA6 A gene on chromosome 2q31.1 that encodes an integrin alpha chain protein which, like all integrins, forms a heterodimer with a beta chain, thereby participating in an array of cell-cell and cell-matrix interactions, playing a major role in cell migration, organ and tissue development, differentiation and metastases. Alpha 6 binds to a beta-1 chain, forming the VLA-6 integrin, a receptor for laminin on platelets, or with beta 4 to form TSP180, a receptor for laminin in epithelial cells, which plays a critical structural role in hemidesmosome.
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