英语词汇“ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 3”的英英意思、用法、释义、翻译、读音、例句、短语、词组-英语词典

单词	ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 3
释义	ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 3 ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 3 An autosomal dominant condition (OMIM:604292) characterised by ectrodactyly of hands and feet, ectodermal dysplasia and facial clefting (the last of which differentiates it from ADULT syndrome). Molecular pathology Caused by defects of TP63, which encodes a p53 transcription factor that acts as a sequence-specific DNA-binding regulator of epithelial morphogenesis and is required for limb formation from the apical ectodermal ridge.
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