CLDN3

CLDN3

A gene on chromosome 7q11.23 that encodes claudin-3, an integral membrane protein of the claudin family, the members of which form part of the tight junction strands providing a continuous seal around cells and serving as a physical barrier to prevent solutes and water from passing freely into the interstitial space.
 
Molecular pathology
Claudin-3 has a low-affinity receptor for Clostridium perfringens enterotoxin.