clinical significance

clinical significance

A change in a patient’s/subject's clinical status that is regarded as important, whether or not it is due to an intervention in the context of a clinical trial. The phrase clinical significance should not be used unless it is operationally defined.

clinical significance

Medtalk A conclusion that an intervention has an effect of practical meaning to Pts and health care providers; even though an intervention is found to have a statistically significant effect, this effect might not be clinically significant