Edinger-Westphal nucleus


Ed·in·ger-West·phal nu·cle·us

(ed'ing-er west'fahl), a small group of preganglionic parasympathetic motor neurons in the midline near the rostral pole of the oculomotor nucleus of the midbrain; the axons of these motor neurons leave the brain with the oculomotor nerve and synapse on the cells of the ciliary ganglion, which in turn innervate the sphincter muscle of the pupil and ciliary muscle. Destruction of this nucleus or its efferent fibers causes maximal paralytic dilation of the pupil; also demonstrated to project fibers to lower levels of the brainstem and all spinal levels. Synonym(s): visceral nuclei of oculomotor nerve [TA]

Edinger-Westphal nucleus

, Westphal-Edinger nucleus (ed′ĭng-ĕr-west′fal″) [Karl Westphal, Ger. neurologist, 1833–1890; Ludwig Edinger, Ger. neurologist, 1855–1918] A nucleus of the visceral motor column in the hindbrain. It lies in the midbrain tegmentum, just beneath the cerebral aqueduct and lateral to the oculomotor nucleus. The Edinger-Westphal nucleus is the origin of preganglionic parasympathetic axons in the oculomotor nerve (CN III) and it innervates the ciliary and pupillary constrictor muscles of the eye.

Edinger,

Ludwig, German anatomist, 1855-1918. Edinger-Westphal nucleus - a small group of preganglionic parasympathetic motor neurons in the midline near the rostral pole of the oculomotor nucleus of the midbrain.

Westphal,

Karl Freiderich Otto, German neuranatomist and psychiatrist, 1833-1890. Edinger-Westphal nucleus - see under EdingerErb-Westphal sign - see under ErbStrümpell-Westphal disease - Synonym(s): Wilson diseaseWestphal ataxia - Synonym(s): Westphal-Leyden syndromeWestphal disease - Synonym(s): Wilson diseaseWestphal phenomenon - Synonym(s): Erb-Westphal signWestphal pseudosclerosis - Synonym(s): Wilson diseaseWestphal pupillary reflex - Synonym(s): Piltz signWestphal sign - Synonym(s): Erb-Westphal signWestphal-Erb sign - Synonym(s): Erb-Westphal signWestphal-Leyden syndrome - absence of knee jerk reflex characteristic of neurosyphilitic disease. Synonym(s): Leyden ataxia; Westphal ataxiaWestphal-Piltz phenomenon - Synonym(s): Piltz signWestphal-Strümpell pseudosclerosis - Synonym(s): Wilson disease