cryopyrin-associated periodic syndromes

A range of autoinflammatory disorders—e.g., familial cold autoinflammatory syndrome (FCAS, aka familial cold-induced urticaria), Muckle-Wells syndrome, and neonatal-onset multisystem inflammatory disease (NOMID, aka chronic infantile neurologic cutaneous and articular syndrome [CINCA])—which share many clinical features (e.g., fever, rash, joint pain, conjunctivitis, headaches, general malaise).
Management
Monoclonal antibodies against IL 1 beta (e.g., canakinumab), other IL-1 binding proteins (e.g., rilonacept), or IL-1 receptor antagonist (e.g., anakinra).

单词	cryopyrin-associated periodic syndromes
释义	cryopyrin-associated periodic syndromes cryopyrin-associated periodic syndromes A range of autoinflammatory disorders—e.g., familial cold autoinflammatory syndrome (FCAS, aka familial cold-induced urticaria), Muckle-Wells syndrome, and neonatal-onset multisystem inflammatory disease (NOMID, aka chronic infantile neurologic cutaneous and articular syndrome [CINCA])—which share many clinical features (e.g., fever, rash, joint pain, conjunctivitis, headaches, general malaise). Management Monoclonal antibodies against IL 1 beta (e.g., canakinumab), other IL-1 binding proteins (e.g., rilonacept), or IL-1 receptor antagonist (e.g., anakinra).
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