单词 | aortic regurgitation |
释义 | aortic regurgitationaortic regurgitationaortic regurgitationregurgitation[re-ger″jĭ-ta´shun]a·or·tic re·gur·gi·ta·tionaortic regurgitationaortic insufficiencyThe reflow of blood back from the aorta into the left ventricle due to incompetency of the aortic valve.Clinical findings Dyspnoea on exertion, orthopnea, fatigue, ± angina, increased pulse pressure, systolic hypertension with increased afterload on left ventricle. Aetiology Congenital or acquired valve defect of either the aortic leaflets (infectious endocarditis, rheumatic fever) or the aortic root (annuloaortic ectasia, Marfan syndrome, aortic dissection, collagen vascular disease, syphilis). Examination Increased pulse pressure (Corrigan’s pulse, Hill sign, Musset sign, Quincke’s pulse), systolic murmur, diastolic rumble (Austin Flint murmur over cardiac apex). Workup Doppler echocardiography to estimate severity of AR, confirmed by aortography. Management Early valve replacement surgery, guided by the ‘55 rule’—i.e., performed when the ejection fraction is < 55% and/or the end-systolic dimension = 55 mm. aortic regurgitationAortic insufficiency Cardiology The reflow of blood back from the aorta into the left ventricle due to incompetency of the aortic valve Etiology Congenital or acquired valve defect of either the aortic leaflets–infectious endocarditis, rheumatic fever, or the aortic root–annuloaortic ectasia, Marfan syndrome, aortic dissection, collagen vascular disease, syphilis Clinical DOE, orthopnea, fatigue, ± angina, ↑ pulse pressure, systolic HTN with ↑ afterload on left ventricle Examination ↑ pulse pressure–Corrigan's pulse, Hill sign, Musset sign, Quincke's pulse; systolic murmur, diastolic rumble–Austin Flint murmur over cardiac apex Workup Doppler echocardiography to estimate severity of AR, confirmed by aortography Management Early valve replacement surgery, guided by the '55 rule'–performed when the ejection fraction is < 55% and/or the end-systolic dimension is ≥ 55 mm. Cf Aortic stenosis.a·or·tic re·gur·gi·ta·tion(ā-ōr'tik rē-gŭr'ji-tā'shŭn)Synonym(s): aortic insufficiency, Corrigan disease. aortic regurgitationAbnormal back flow of blood from the aorta through the aortic valve. In developing countries the valvular defect is mainly due to as complication of rheumatic fever; in Western countries the defect is usually congenital.Corrigan,Sir Dominic John, Irish pathologist and clinician, 1802-1880. |
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