clonality


clonality

 [klo-nal´ĭ-te] the ability to be cloned.

clonality

A state of proliferation determined by the cell(s) of origin; daughter cells arising from multiple cells–ie polyclonal are reactive in nature, while those arising from a single cell–ie monoclonal are neoplastic; determining clonality is important in treating a disease, and understanding its physiopathology, and can be assessed in ♀ by molecular analysis of the patterns of X chromosome inactivation. See Clonal analysis.