释义 |
DictionarySeetheoryclonal selection theory
clonal selection theory[¦klōn·əl si′lek·shən ‚thē·ə·rē] (immunology) Theory to explain the specificity of the adaptive immune response according to which there is a large pool of lymphocytes, each having genetically predetermined specificity for only one of a vast array of possible antigens. Upon encountering an antigen, the lymphocytes sensitive to it reproduce much more rapidly than the others, thus leading to a build-up of antigen-specific cells large enough to mount the response. clonal selection theory
clo·nal se·lec·tion the·o·rya theory which states that each lymphocyte has membrane-bound immunoglobulin receptors specific for a particular antigen and after the receptor is engaged, proliferation of the cell occurs such that a clone of antibody-producing cells (plasma cell) is produced.clo·nal se·lec·tion the·or·y (klō'năl sĕ-lek'shŭn thē'ŏr-ē) A theory that states that each lymphocyte has membrane-bound immunoglobulin receptors specific for a particular antigen and after the receptor is engaged, proliferation of the cell occurs such that a clone of antibody producing cells (plasma cell) is produced. |