单词 | clostridium difficile |
释义 | Clostridium difficileClostridium difficile(dɪˈfɪsɪli; ˌdɪfɪˈsiːl)Clostridium difficileClos·trid·i·um dif·fi·cileAvoid the mispronunciation dĭf-ĭ-sēl' of this Latin word, which is correctly pronounced dĭ-fĭs'ĭ-lē.Clostridium difficile(dĭf′ĭ-sēl′, dĭf′ĭ-sēl′, dĭf′ĭ-kē′lā)Clostridium difficileA common cause of bacterial colitis; it is the causative agent in 99% of pseudomembranous colitis, and 20-30% of antibiotic-associated diarrheaClos·trid·i·um dif·fi·ci·le(klos-trid'ē-ŭm di-fis'i-lē)Synonym(s): C-Diff, CDT. Clostridium difficileA fecal organism endemic in hospitals and responsible for the majority of hospital-acquired cases of diarrhoea in elderly patients. Its prevalence in hospital is largely due to the high levels of antibiotic usage. Bowel infection can be cleared by oral treatment with the antibiotic vancomycin which is not appreciably absorbed into the bloodstream. Up to 40 percent of hospitalized patients are colonized with this organism. Only about 3 percent of healthy adults carry it. A previously uncommon strain with variations in toxin genes has emerged as a cause of C. difficile -associated disease.See C. Diff |
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