| Acronym | Definition |
|---|
| ESPE➣Escuela Politecnica del Ejercito (Spanish: Army Polytechnic Institute; Ecuador) |
| ESPE➣European Society for Paediatric Endocrinology |
| ESPE➣European Society for Population Economics (est. 1986; Spain) |
| ESPE➣Exercise Science and Physical Education (education program) |
| ESPE➣Electro Sensitive Protection Equipment |
| ESPE➣End State Peacetime Establishment |
| ESPE➣Envision Schools Project Exchange (online workspace) |