anaplastic carcinoma

an·a·plas·tic car·ci·no·ma

carcinoma with an absence of epithelial structural differentiation.

anaplastic carcinoma

An aggressive epithelial malignancy which lacks histologic criteria required to confirm its embryonic lineage. Anaplastic carcinomas often respond poorly to excision, chemotherapy and radiotherapy. They generally lack architectural landmarks and are divided into small cell, intermediate cell, giant cell, spindle cell and mixed cell types, and occur in the lungs, thyroid, oesophagus and elsewhere.

Prognosis
Generally poor; 6-month survival is the norm.

Aetiology
Unknown; possibly linked to radiation exposure.

单词	anaplastic carcinoma
释义	anaplastic carcinoma an·a·plas·tic car·ci·no·ma carcinoma with an absence of epithelial structural differentiation. anaplastic carcinoma An aggressive epithelial malignancy which lacks histologic criteria required to confirm its embryonic lineage. Anaplastic carcinomas often respond poorly to excision, chemotherapy and radiotherapy. They generally lack architectural landmarks and are divided into small cell, intermediate cell, giant cell, spindle cell and mixed cell types, and occur in the lungs, thyroid, oesophagus and elsewhere. Prognosis Generally poor; 6-month survival is the norm. Aetiology Unknown; possibly linked to radiation exposure.
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