| Acronym | Definition |
|---|
| ESPL➣Esplanada (Canada Post road designation) |
| ESPL➣Eastern Shore Public Library (Accomac, VA) |
| ESPL➣Empire Series Paintball League (Ontario, Canada) |
| ESPL➣End-Systolic Pressure-Length Relation (anesthesia) |
| ESPL➣E-Sports Professional League |
| ESPL➣East Smithfield Public Library (Smithfield, RI) |