AP1S1

AP1S1

A gene on chromosome 7q22.1 that encodes a subunit of the trans-Golgi network clathrin-associated protein complex AP-1, which is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. The vesicles are involved in endocytosis and Golgi processing; the AP complexes recruit clathrin to membranes and recognise sorting signals within the cytosolic tails of transmembrane cargo molecules.