AP3B1

A gene on chromosome 5q14.1 that encodes a subunit of the heterotetrameric AP3 complex, a protein complex composed of two large subunits (delta and beta), a medium subunit (mu), and a small subunit (sigma). AP3 plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes, as well as in biogenesis of melanosomes, platelet dense granules and lysosomes. AP3 interacts with clathrin, facilitating the budding of vesicles from the Golgi membrane.
Molecular pathology
AP3B1 mutations are associated with the Hermansky-Pudlak syndrome, which is characterised by defective lysosome-related organelles.

单词	ap3b1
释义	DictionarySeepeEncyclopediaSeeHPS AP3B1 AP3B1 A gene on chromosome 5q14.1 that encodes a subunit of the heterotetrameric AP3 complex, a protein complex composed of two large subunits (delta and beta), a medium subunit (mu), and a small subunit (sigma). AP3 plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes, as well as in biogenesis of melanosomes, platelet dense granules and lysosomes. AP3 interacts with clathrin, facilitating the budding of vesicles from the Golgi membrane. Molecular pathology AP3B1 mutations are associated with the Hermansky-Pudlak syndrome, which is characterised by defective lysosome-related organelles. FinancialSeePe
随便看	code abuse prevention system code access security code adam code administrators association of kentucky code alarm glass break sensor code alpha code amber code analysis plugin code analysis repository and modelling for e-neuroscience code and time-division multiple access code and unit test code and unit test walkthrough code antidopage du mouvement olympique code application notice code applications and maintenance program code area code assessment & maintenance program code assignment with dynamic partition and buffering code assure management center code, astronomical code atlas code auditing reporting application code aurora forum code available code base