familial hyperlipoproteinemia type IV

fa·mil·i·al hy·per·lip·o·pro·te·in·e·mi·a type IV

[MIM*144600] plasma levels of VLDL, pre-β-lipoproteins and triglycerides are increased on a normal diet, but β-lipoproteins, cholesterol, and phospholipids are normal; hypertriglyceridemia is induced by a high carbohydrate diet; may be accompanied by abnormal glucose tolerance and susceptibility to ischemic heart disease; probably autosomal dominant inheritance but genetic heterogeneity is a possibility. Synonym(s): carbohydrate-induced hyperlipemia, familial hyperprebetalipoproteinemia, familial hypertriglyceridemia (2)