familial recurrent polyserositis

fa·mil·i·al par·ox·ys·mal pol·y·ser·o·si·tis

[MIM*249100] transient recurring attacks of abdominal pain, fever, pleurisy, arthritis, and rash; the condition is asymptomatic between attacks; autosomal recessive inheritance, caused by mutation in the marenostrin gene on 16p. There is an autosomal dominant form [MIM*134610] in which amyloidosis is common. Synonym(s): benign paroxysmal peritonitis, familial Mediterranean fever, familial recurrent polyserositis, Mediterranean fever (2) , periodic peritonitis, periodic polyserositis

recurrent polyserositis

(1) Familial Mediterranean fever (see there), OMIM:249100. 
(2) The term has also be used for any recurring inflammation of serous membranes.

Patient discussion about familial recurrent polyserositis

Q. Can Familial Mediterranean Fever (FMF) cause a heart enlargement? A friend of mine is suffering from FMF. its usually doesn't bother him that much and when it dose the symptoms are stomach ache and fever. he has no heart symptoms and takes no medications.his physician told him that because of the FMF he might suffer from a heart enlargement, and that he should take some oral medications daily to prevent it.how can it be?A. This question can't be answered with a strict yes or no.
although FMF on its own can't cause heart enlargement, FMF can cause amyloidosis because of the recurrent inflammation. this may lead to enlargement of the heart which is a severe disease.
the good side is that taking medication can decrease the chance of the cardiac enlargement.

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