| Acronym | Definition |
|---|
| CSX➣Chessie Seaboard Multiplier (railroad transportation company) |
| CSX➣Cayman Islands Stock Exchange |
| CSX➣Changsha, China (Airport Code) |
| CSX➣Counter-Strike Xbox (gaming) |
| CSX➣CommonStore for Exchange (IBM) |
| CSX➣Cardiac-Specific Homeobox |
| CSX➣Seaboard Coastline Railroad |
| CSX➣Car Stock Exchange (game; Edmonds Inc.) |