defensin

A small (29 to 34 amino acid) cationic peptide produced in neutrophils and epithelial cells, which may be involved in nonspecific response to microbes.
Types
ß-defensin 1—expressed in alveolar epithelia of normal individuals, but not in patients with cystic fibrosis.
ß-defensin 2—first identified in the skin of patients with psoriasis who have a decreased susceptibility to skin infections.

defensin

(dē-fĕn′sĭn) [term coined by Robert I. Lehrer, U.S. physician, b. 1938] Destructive peptides (groups of amino acids) found in the granules of neutrophils and other phagocytic cells that kill bacteria and fungi by destroying their membranes. Defensins are active against bacteria, fungi, and enveloped viruses in vitro. They may contribute to host defenses against susceptible organisms.

单词	defensin
释义	defensin defensin A small (29 to 34 amino acid) cationic peptide produced in neutrophils and epithelial cells, which may be involved in nonspecific response to microbes. Types ß-defensin 1—expressed in alveolar epithelia of normal individuals, but not in patients with cystic fibrosis. ß-defensin 2—first identified in the skin of patients with psoriasis who have a decreased susceptibility to skin infections. defensin (dē-fĕn′sĭn) [term coined by Robert I. Lehrer, U.S. physician, b. 1938] Destructive peptides (groups of amino acids) found in the granules of neutrophils and other phagocytic cells that kill bacteria and fungi by destroying their membranes. Defensins are active against bacteria, fungi, and enveloped viruses in vitro. They may contribute to host defenses against susceptible organisms.
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