aldehyde reductase

al·co·hol de·hy·dro·gen·ase (NADP+)

(al'kŏ-hol dē-hī-droj'e-nās), An oxidoreductase that reversibly converts alcohols to aldehydes (or ketones) with NADP+ as hydride acceptor. Synonym(s): aldehyde reductase

ADH1A

A gene on chromosome 4q21-23 that encodes class-I alcohol dehydrogenase, alpha subunit, a member of the alcohol dehydrogenase family, which metabolise various substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids and lipid peroxidation products. The encoded protein plays a major role in ethanol catabolism and is highly expressed in adults livers.