| 释义 |
DictionarySeeglomerulosclerosisfocal segmental glomerulosclerosis
glomerulosclerosis [glo-mer″u-lo-sklĕ-ro´sis] arteriolar nephrosclerosis.diabetic glomerulosclerosis (intercapillary glomerulosclerosis) a degenerative complication of diabetes mellitus in which there is glomerular mesangial expansion with either diffuse lesions or nodular (Kimmelstiel-Wilson) lesions; symptoms include albuminuria, nephrotic edema, hypertension, renal insufficiency, and retinopathy. The type with nodular lesions is also called Kimmelstiel-Wilson syndrome.focal segmental glomerulosclerosis focal sclerosing lesions of the renal glomeruli, with proteinuria, hematuria, hypertension, and the nephrotic syndrome" >nephrotic syndrome; it may be idiopathic or secondary to another condition. Called also focal glomerular sclerosis.fo·cal seg·men·tal glo·mer·u·lo·scle·ro·sissegmental collapse of glomerular capillaries with thickened basement membranes and increased mesangial matrix; seen in some glomeruli of patients with nephrotic syndrome or mesangial proliferative glomerulonephritis.fo·cal seg·men·tal glo·mer·u·lo·scle·ro·sis (fō'kăl seg-men'tăl glo-mer'yū-lō-skler-ō'sis) Segmental collapse of glomerular capillaries with thickened basement membranes and increased mesangial matrix; seen in some glomeruli of patients with nephrotic syndrome or mesangial proliferative glomerulonephritis. focal segmental glomerulosclerosisAn irreversible form of glomerular injury often seen in patients with a history of injection drug use or acquired immunodeficiency syndrome.See also: glomerulosclerosisAcronymsSeeFSG |