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单词 dopa
释义

dopa


do·pa

D0343000 (dō′pə)n. An amino acid, C9H11NO4, that occurs widely in animals and plants. In humans and other mammals, it is formed in the liver from tyrosine and converted to dopamine in the brain.
[d(ihydr)o(xy)p(henyl)a(lanine).]

dopa

(ˈdəʊpə) n (Biochemistry) See L-dopa

do•pa

(ˈdoʊ pə)

n. an amino acid, C9H11NO4, formed from tyrosine in the liver during melanin and epinephrine biosynthesis. Compare L-dopa. [< German Dopa (1917), contraction of 3, 4-Dioxyphenylanin]
Thesaurus
Noun1.dopa - amino acid that is formed in the liver and converted into dopamine in the braindihydroxyphenylalanineamino acid, aminoalkanoic acid - organic compounds containing an amino group and a carboxylic acid group; "proteins are composed of various proportions of about 20 common amino acids"Bendopa, Brocadopa, Larodopa, L-dopa, levodopa - the levorotatory form of dopa (trade names Bendopa and Brocadopa and Larodopa); as a drug it is used to treat Parkinson's disease

Dopa


dopa

[′dō·pə] (biochemistry) dihydroxyphenylalanine

Dopa

 

3,4-dihydroxyphenylalanine, C6H3(OH)2CH2CH(NH2)COOH, an amino acid.

In animals, dopa is one of the precursors in the chain of catecholamine biosynthesis. It is produced in tissues by the oxidation of tyrosine. In animals, plants, and some microorganisms, dopa is the first intermediate product in the synthesis of melanins. Healthy persons excrete from 50 to 55 μg of dopa daily with the urine; the amount increases in the presence of a neuroblastoma, a kind of malignant tumor. An inhibitor of dopa decarboxylase, a-methyldopa (Aldomet), is used in the treatment of parkinsonism and hypertension.

REFERENCES

Matlina, E. Sh., and V. V. Men’shikov. Klinicheskaia biokhimiia katekholaminov. Moscow, 1967.
Grollman, A. Klinicheskaia endokrinologiia i ee fiziologicheskie osnovy. Moscow, 1969. (Translated from English.)

dopa


dopa

 [do´pah] a compound produced by oxidation of tyrosine by tyrosinase; it is the precursor of dopamine" >dopamine and an intermediate product in the biosynthesis of norepinephrine, epinephrine, and melanin. The naturally occurring form is l-dopa" >l-dopa (see levodopa), and is used to treat parkinson's disease and other forms of parkinsonism.

do·pa

, DOPADopa (dō'pă), An intermediate in the catabolism of l-phenylalanine and l-tyrosine, and in the biosynthesis of norepinephrine, epinephrine, and melanin; the l form, levodopa, is biologically active. See: dopa reaction. Synonym(s): 3, 4-dihydroxyphenylalanine

dopa

(dō′pə)n. An amino acid, C9H11NO4, that occurs widely in animals and plants. In humans and other mammals, it is formed in the liver from tyrosine and converted to dopamine in the brain.

do·pa

, DOPA (dō'pă) An intermediate in the catabolism of l-phenylalanine and l-tyrosine, and in the biosynthesis of norepinephrine, epinephrine, and melanin; the l form, levodopa, is biologically active.

DOPA (dihydroxy phenylalanine)

a precursor in the biochemical PATHWAY leading to MELANIN formation in animals. DOPA is not metabolized in individuals with ALBINISM.

DOPA

The common name for a natural chemical (3, 4-dihydroxyphenylalanine) made by the body during the process of making melanin.Mentioned in: Albinism

do·pa

, DOPA (dō'pă) Intermediate in catabolism of l-phenylalanine and l-tyrosine and in biosynthesis of norepinephrine, epinephrine, and melanin.

DOPA


AcronymDefinition
DOPADihydroxyphenylalanine
DOPADirection de l'Organisation et du Personnel des Armées (French: Directorate of the Organization and Personnel of the Armed Forces; Benin)
DOPADeleting Online Predators Act of 2006
DOPADepartment of Public Administration
DOPADesignated Official Planning Agency
DOPADairy Outreach Program Area (Texas)
DOPADepartment of Personnel Administration

dopa


Related to dopa: dopamine, DOPA decarboxylase
  • noun

Synonyms for dopa

noun amino acid that is formed in the liver and converted into dopamine in the brain

Synonyms

  • dihydroxyphenylalanine

Related Words

  • amino acid
  • aminoalkanoic acid
  • Bendopa
  • Brocadopa
  • Larodopa
  • L-dopa
  • levodopa
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